Sometimes the best way to manage an animal’s health in the present is to look into the past. With the help of a FONZ Conservation Grant — funded by the Round Up for Conservation Program — that’s what Natalia Prado and her team of Smithsonian scientists are planning to do with Asian and African elephants at zoos across the country, including those at the Smithsonian’s National Zoo.
The family history of every animal is unique and leads to its distinct genomic makeup. With the funds from the FONZ Conservation Grant, Prado and her team will work to generate the genomic tools needed to decode elephants’ genetic histories across the United States, to address fundamental questions about individual and population health. With the information they receive, the team will develop the tools necessary to learn about each elephant’s family tree. This information could lead to a better understanding of numerous conditions that elephants exhibit in human care, including infertility, foot and joint problems, and susceptibility to diseases such as elephant endothelial herpes virus (EEHV) and tuberculosis.
Over the next year, the scientists will map the entire genomes of nine elephants, including five from the Zoo’s herd — Kandula, Shanthi, Ambika, Bozie and Maharani. The success of this mapping will set the groundwork for the development of tools needed to screen about 300 elephants for shared genetic traits.
If Smithsonian scientists can disentangle the effects of environment versus genetics, or nature versus nurture, using these genomic tools, it could make a world of difference for elephants not just in human care but also in the wild.